Patients taking more than 3 grams of omega-3 fatty acids from supplements should do so only under a physician’s care. High intakes could cause excessive bleeding in some people. An article in the American Journal of Clinical Nutrition in July 2003 by Peter Marckmann from Denmark reports on various European studies that show an average daily intake of 50 grams of fish was reported to cut coronary heart disease mortality rates in half. He states that fish may be more beneficial than fish oil for three reasons: (1) Fish contains potentially more cardioprotective nutrients such as selenium, various natural antioxidants and fish protein that are not present in fish oil. (2) Fish intake may modify meals in a healthy direction: fish typically replaces red meat and fish is often consumed with specific foods such as mustard, dill and broccoli that may be healthy, but otherwise seldom eaten. (3) Fish is an integrated part of the diet, whereas fish-oil supplements add pure fat to the diet with no other benefits. Overall, fish is an excellent source of nutrients and unless it comes from heavily polluted waters, can fit into a healthy, cardioprotective diet that is low in saturated fat.