Animal Use Amendments

If a significant change from a previously approved protocol is to be made, a formal amendment must be submitted for review to the ACFC.

Significant changes include:

• Change in species
• Change in drugs administered
• Change in method of anesthesia
• Change in method of euthanasia
• Inclusion of new surgical procedures
• Procedures that cause pain or distress in conscious animals
• Prolonged restraint
• Use of hazardous substances that involve possible exposure of personnel or animals in the animal facility.

The following changes would NOT be considered significant:

• Changes in strain, stock, or breed of animal
• Moving an animal from one approved animal facility to another
• Changes in in vitro procedures involving animal tissues
• Changes in funding agency, grant or account.

Faculty are encourage to call either Dr. Michael J. Fennell or Dr. Robert L. Harris relative to questions on whether a change requires an amendment or not. In some instances, a new protocol may be required. Additional information on the review process for the use of animals can be found at http://ORSP.rutgers.edu/animal.asp.